IDENTIFYING DETERMINANTS OF CULLIN BINDING SPECIFICITY AMONG THE THREE FUNCTIONALLY DIFFERENT DROSOPHILA MELANOGASTER ROC PROTEINS VIA DOMAIN SWAPPING.

Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain swapping.

BackgroundCullin-dependent E3 ubiquitin ligases (CDL) are key regulators of protein destruction that participate in a wide range of cell biological processes.The Roc subunit of CDL contains an evolutionarily conserved RING domain that binds ubiquitin charged E2 and is essential for ubiquitylation.Drosophila melanogaster contains three highly relate

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What you learn is more than what you see: What can sequencing effects tell us about inductive category learning?

Inductive category learning takes place across time.As such, it is not surprising that the sequence in which information is studied has an impact in what is learned and how efficient learning is.In this paper we review research on different learning sequences and how this impacts learning.We analyze different aspects of interleaved (frequent altern

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